Analysis of options for prescribing hormone replacement therapy after thyroid organ-sparing surgery

نویسندگان

چکیده

Background. Performing thyroid organ-sparing surgery primarily aims to preserve the quality of life. Organ-sparing should be understood as hemithyroidectomy with mandatory removal isthmus and pyramidal lobe (if present). The choice one or another concept prescribing hormone replacement therapy remains debatable. purpose study is determine proportion patients who do not need levothyroxine after on gland, among those were prescribed immediately month discharge from hospital, well analyze factors causing hypothyroidism in people hemithyroidectomy. Materials methods. first group included 82 hospital. second 61 administration was postponed for month. A operation, clinical examinations monitoring thyroid-stimulating free thyroxine indicators performed. Results. After observation, 72 (87.8%) continued take levothyroxine, 8 (13.1%) persons began it. In group, there a moderate direct correlation between level before dose (Spearman’s coefficient 0.304, p=0.009). It found that chances continuing taking 47 times higher than group. significantly started (87.8±3.6% vs. 13.1±3.5%, p<0.0001, Fisher’s exact test). Conclusions. Among hemithyroidectomy, 12.2% did continue whom 86.9% require use future. volume remnant ≤ 3.67 cm3 can considered predictor occurrence future, high risk therapy. such factor ratio body weight provide statistically reliable data its postoperative period.

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ژورنال

عنوان ژورنال: Mìžnarodnij endokrinologì?nij žurnal

سال: 2023

ISSN: ['2224-0721', '2307-1427']

DOI: https://doi.org/10.22141/2224-0721.19.3.2023.1265